Take a look at this video of Trey Anastasio of Phish at the Grammy's. Apparently, he brought his sister Very sweet, and you can see the family resemblance.
Why did he bring his sister to the Grammy's? Because he's been fighting with his wife. Apparently, they were in an argument about his drug problem the night he was arrested in Whitehall, NY (whole story here). Then he gets busted and is even more trouble because of his drugs. I guess his wife is REALLY pissed!
Perhaps home life is just too quiet for him. He's spent most of his adult life on tour with Phish. Having a wife and kids always went hand and hand with being away from home. Staying home more often must be a difficult switch. I hope this means reunion!